R454B
Refrigerant
A 22LB professional-use cylinder for approved R454B air-conditioning, heat-pump and chiller equipment.
- ✓Lower-GWP option for compatible modern HVAC and heat-pump equipment.
- ✓A2L refrigerant blend with zero ozone-depletion potential.
- ✓Factory-sealed, non-refillable disposable cylinder for professional use.
Technical details at a glance.
22LB R454B Refrigerant Gas
For systems expressly designed, listed and approved by the manufacturer for R454B refrigerant.
Zeotropic HFO/HFC blend
Disposable supply cylinder
Mildly flammable — trained handling required
Lower impact than older high-GWP options
Non-ozone-depleting formulation
Confirm OEM requirements before service
Nominal refrigerant blend
Not a universal drop-in replacement
Where R454B is used.
Compatibility must always be verified against the equipment nameplate and the original manufacturer’s documentation.
Residential AC
Approved mini-split, multi-split, ducted and packaged comfort systems.
Light Commercial
Listed packaged and direct-expansion air-conditioning equipment.
Heat Pumps
Reversible heating and cooling units engineered specifically for R454B.
DX Chillers
Compatible chillers and cooling equipment approved by the OEM.
Made for professional service work.

Lower-GWP direction
R454B supports approved new equipment with lower environmental impact compared with older high-GWP alternatives.

Professional handling
Built for qualified HVAC professionals following equipment manuals, SDS and required safety procedures.

Clear product verification
Labeling and cylinder format help technicians verify product details before storage, transport and service work.
R454B FAQ
Quick product guidance for buyers and qualified HVAC professionals.
Contact supportProfessional supply. Straightforward support.
Free U.S. shipping and secure checkout from Frostlino.





