FrostlinoRefrigerantsR454B 22LB
Professional HVAC Supply
22LB CYLINDER
Next-generation refrigerant

R454B
Refrigerant

A 22LB professional-use cylinder for approved R454B air-conditioning, heat-pump and chiller equipment.

★★★★★ Professional-grade HVAC supply
$99.94
$233.00
SAVE $133.06
In stock · Free U.S. shipping
  • Lower-GWP option for compatible modern HVAC and heat-pump equipment.
  • A2L refrigerant blend with zero ozone-depletion potential.
  • Factory-sealed, non-refillable disposable cylinder for professional use.
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Product Profile

Technical details at a glance.

Frostlino Technical Series

22LB R454B Refrigerant Gas

For systems expressly designed, listed and approved by the manufacturer for R454B refrigerant.

RefrigerantR454B

Zeotropic HFO/HFC blend

Net Weight22LB / 10KG

Disposable supply cylinder

Safety ClassA2L

Mildly flammable — trained handling required

GWPApprox. 466

Lower impact than older high-GWP options

ODPZero

Non-ozone-depleting formulation

Typical LubricantPOE

Confirm OEM requirements before service

CompositionR32 / R1234yf

Nominal refrigerant blend

UseApproved Equipment

Not a universal drop-in replacement

Compatible Applications

Where R454B is used.

Compatibility must always be verified against the equipment nameplate and the original manufacturer’s documentation.

Residential AC

Approved mini-split, multi-split, ducted and packaged comfort systems.

Light Commercial

Listed packaged and direct-expansion air-conditioning equipment.

Heat Pumps

Reversible heating and cooling units engineered specifically for R454B.

DX Chillers

Compatible chillers and cooling equipment approved by the OEM.

Product Guidance

Made for professional service work.

1

Lower-GWP direction

R454B supports approved new equipment with lower environmental impact compared with older high-GWP alternatives.

2

Professional handling

Built for qualified HVAC professionals following equipment manuals, SDS and required safety procedures.

3

Clear product verification

Labeling and cylinder format help technicians verify product details before storage, transport and service work.

Questions Answered

R454B FAQ

Quick product guidance for buyers and qualified HVAC professionals.

Contact support
No. R454B is used in equipment specifically engineered and approved for it.
No. Mixing refrigerants can affect pressure, performance and service reliability.
R454B is classified as A2L. It should be handled by trained professionals.
Only equipment approved by the manufacturer for R454B refrigerant.

Professional supply. Straightforward support.

Free U.S. shipping and secure checkout from Frostlino.

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